The median home price in West Virginia is $178,702, 57% below the $420,000 national median. With a median household income of $60,798, the price-to-income ratio is 2.9x.
West Virginia's 0.51% average property tax rate runs below the 1.1% national average, working out to $76/month on the median home here.
West Virginia levies a state income tax of 2.22%–4.82% on top of the $1,064/month this mortgage runs. Model your real after-tax take-home before deciding how much payment you can carry.
West Virginia's cost of living index is 88, below the 100 national baseline. That's on top of the housing numbers above, not instead of them.
West Virginia's median home price runs 9% lower than Mississippi: $196,333 there versus $178,702 here.