Statewide, Missouri's median home price runs $245,000, 42% below the $420,000 national median. The 4.0x price-to-income ratio here is measured against a $61,000 median household income.
Property taxes in Missouri average 0.97% of assessed value, below the 1.1% national average. On the median home, that's $2,377 a year, or $198 added to the monthly payment.
Missouri levies a state income tax of 2%–4.95% on top of the $1,577/month this mortgage runs. Model your real after-tax take-home before deciding how much payment you can carry.
Day-to-day expenses statewide track at 89 against the national 100 baseline, below average once you look past the mortgage payment itself.
Missouri's median home price runs 2% lower than Nebraska: $250,000 there versus $245,000 here.