$420,000 buys the median home in Raleigh right now. With 20% down, that's a $84,000 down payment and a $336,000 loan, set against a $78,000 median household income.
Raleigh's 0.83% property tax rate runs below the 1.1% national average. That's $291/month on the median home here, not a rounding error against the mortgage payment.
North Carolina levies a state income tax on top of the $2,643/month this mortgage runs. Model your real after-tax take-home before deciding how much payment you can carry.
Raleigh's cost of living index is 105, above the 100 national baseline. That's on top of the housing numbers above, not instead of them.
Raleigh's median home price runs 8% higher than nearby Charlotte: $390,000 there versus $420,000 here.