Buying the median home in Santa Fe means financing $520,000. Against the area's $60,000 median household income, that works out to a 8.7x price-to-income ratio.
At a 0.48% effective rate, Santa Fe property taxes add $208 to the monthly payment on the median home, $2,496 a year in total.
New Mexico levies a state income tax on top of the $3,121/month this mortgage runs. Model your real after-tax take-home before deciding how much payment you can carry.
Santa Fe's cost of living index is 108, above the 100 national baseline. That's on top of the housing numbers above, not instead of them.
Santa Fe's median home price runs 68% higher than nearby Albuquerque: $310,000 there versus $520,000 here.